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Readers of Evidence Based Birth Give Back!

Dear Readers, 

Please consider donating to Improving Birth in honor of Evidence Based Birth.com!

Please consider donating to Improving Birth in honor of Evidence Based Birth.com!

Just over a year ago, I began publishing articles on Evidence Based Birth with the goal of providing you with easy-to-access, accurate, fact-based information about childbirth. I did not want to (and I did not try) to earn any money off my blog through advertising. In fact, I fund the significant costs of running the blog out of my own pocket. This blog is not my job, but it is not just a hobby, either. It has been a labor of love. It is my gift to you.

But last fall I wanted to do even more. I was putting evidence-based information out there on my blog for moms and families to find, but I felt led to find a group with whom I could actively advocate for an improvement in maternity care. So I joined the board of directors of ImprovingBirth.org in a non-paid volunteer position.

For those of you who don’t know, ImprovingBirth.org is a non-profit organization, made up of mothers and those who care for us, whose mission is to bring evidence-based care and humanity to childbirth. As you might guess, this mission is very close to my heart!

This Labor Day 2013, ImprovingBirth.org is organizing an international Rally to Improve Birth. On September 2, 2013, moms, dads, children, healthcare providers, and birth professionals will be rallying at more than 200 locations across the U.S. and internationally, all with the same message– “We can do better.”

I want to make it clear that this movement is not about natural birth vs. medicated birth. It’s not about hospital birth vs. home birth or birth center birth. It’s about women being capable of making safer, more informed decisions about their care and that of their babies, when they are given full and accurate information about their care options, including the potential harms, benefits, and alternatives.

On September 3, we are rallying to raise awareness of the problems with our maternity care systems. But we also raising awareness of a solution. We– mothers and those who care for us– are part of the solution! If we raise all our voices at the same time, change will come!

So if you’ve ever been touched by an Evidence Based Birth article– if you’ve ever been able to use or pass on information that I have freely provided for you, I would like to ask that you consider making a donation to ImprovingBirth.org in honor of Evidence Based Birth. To donate, click here.

I have set a goal of funding 30 Rally sites at a cost of $75 each. If just half of my email followers donated $10, we would easily surpass our goal of $3,000! Or, if you are able to be really generous, consider funding an entire rally location by donating $75.

To give you a little extra motivation to donate, once we reach the halfway point ($1,500) I will give a hint on Facebook as to what my next big Evidence Based Birth article will be. When we reach $3,000, I will release the title of the next article along with a preview!

If you make a donation, you will receive a receipt for your tax-deductible donation. The recipient organization is “Better Beginnings”– this is the organization that is fiscally sponsoring ImprovingBirth.org while we wait for our official non-profit number (there is a 1 year wait to get official status).

To donate, click here.

Thank you for joining with me in donating to Improve Birth!

Sincerely,

Rebecca Dekker
Founder, www.evidencebasedbirth.com

For more information on this year’s rally, and to see if there is going to be a rally near you, visit www.RallyToImproveBirth.com

 

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What is the Evidence for Induction or C-section for a Big Baby?

What is the Evidence for Induction or C-section for a Big Baby?

By Rebecca Dekker, PhD, RN, APRN of www.evidencebasedbirth.com

Kelly's "little chunk" was born 13 days past his due date and was 9 pounds 7 oz long. After her normal healthy birth, Kelly was told by the nurse that she should have "warned them" that the baby was big because it was "dangerous" to give birth to a big baby with her small frame.

Here is Kelly’s little chunk! He was born 13 days past his due date and was 9 pounds 7 oz long. After her normal healthy birth, Kelly was told by the nurse that she should have “warned them” that the baby was big because it was “dangerous” to give birth to a big baby with her small frame.

What is a big baby?

The medical term for big baby is macrosomia, which literally means “big body.” Some experts consider a baby to be big when it weighs more than 4,000 grams (8 pounds 13 ounces) at birth, and others say a baby is big if it weighs more than 4,500 grams (9 pounds, 15 ounces). A baby is also called “large for gestational age” if its weight is greater than the 90th percentile at birth (Rouse et al. 1996).

How common are big babies?

Big babies are born to about 1 out of 10 women in the U.S. Overall, 8.7% of all babies born at 39 weeks or later weigh between 8 lbs 13 oz and 9 lbs 15 oz, and 1.7% are born weighing 9 lbs 15 oz or more (U.S. Vital Statistics). You can see the percentages listed separately below for women who are diabetic and not diabetic.

Table1a

Among women with gestational diabetes, researchers have found a dose-response relationship between blood sugar at diagnosis (the glucola test) and the baby’s weight. This means that the higher your blood sugar, the more likely you are to have a baby who is large for gestational age (Metzger et al. 2008). However, women who receive treatment for gestational diabetes cut their chances of having a big baby in half (Landon, Spong et al. 2009).

What is routine care for suspected big babies in the U.S.?

With Katie's first child, she ended up with a C-section because she was told her baby could not fit through her pelvis (7 lb 13 oz). She went on to birth her next son  (9 lb) vaginally.

With Katie’s first child, she ended up with a C-section because she was told her baby could not fit through her pelvis (7 lb 13 oz). She went on to birth her next son (9 lb) vaginally.

Although big babies are only born to 1 out of 10 women, the 2013 Listening to Mothers Survey found that 2 out of 3 American women had an ultrasound at the end of pregnancy to determine the baby’s size, and 1 out of 3 were told that their babies were too big. In the end, the average birth weight of these suspected “big babies” was only 7 lbs 13 oz (Declercq, Sakala et al. 2013).

Of the women who were told that their baby was getting big, 2 out of 3 said their care provider discussed inducing labor because of the suspected big baby, and 1 out of 3 said their care provider talked about planning a C-section because of the big baby.

Most of the women whose care providers talked about induction for big baby ended up being induced (67%), and the rest tried to self-induce labor (37%). Nearly 1 in 5 women said they were not offered a choice when it came to induction—in other words, they were told that they must be induced for their suspected big baby.

When care providers brought up planning a C-section for a suspected big baby, 1 in 3 women ended up having a planned C-section. Two out of five women said that the discussion was framed as if there were no other options—that they must have a C-section for their suspected big baby. 

Starting at 10 weeks, Camahta was told she would need a C-section because she was "fat" and the baby was going to be "huge." At 41 weeks, the doctor estimated the baby was close to 10 pounds. Camahta's son was born via a much-needed C-section 2 days later due to cord entanglement. He weighed 5 pounds 14 ounces.

Starting at 10 weeks, Camahta was told she would need a C-section because she was “fat” and the baby was going to be “huge.” At 41 weeks, the doctor estimated the baby was close to 10 pounds. Camahta’s son was born via a much-needed C-section 2 days later due to cord entanglement. He weighed 5 pounds 14 ounces.

In the end, care provider concerns about a suspected big baby were the 4th most common reason for an induction (16% of all inductions), and the 5th most common reason for a C-section (9% of all C-sections). More than half of all moms (57%) believed that an induction is medically necessary if a care provider suspects a big baby. So in the U.S., most women have an ultrasound at the end of pregnancy to estimate the baby’s size, and if the baby appears large, their care provider will usually recommend either an induction or an elective C-section. Is this approach evidence-based?

This approach is based on 4 major assumptions:

  1. Big babies are at higher risk for problems.
  2. We can accurately tell if a baby will be big.
  3. Induction keeps the baby from getting any bigger, which lowers the risk of C-section.
  4. Elective C-sections for big baby are beneficial and don’t have any major risks.

What is the evidence for these assumptions? Are they true? Let’s take a closer look at each one.

Assumption #1: Big babies are at higher risk for problems.

Reality #1: Big babies are at higher risk for temporarily getting their shoulders stuck, but difficulty giving birth to shoulders is unpredictable and permanent injuries are rare. A care provider’s suspicion of a big baby is more harmful than an actual big baby itself.

One of the main problems with big babies is shoulder dystocia (“dis toh shah”) which means difficulty birthing the baby’s shoulders. In articles that were written about shoulder dystocia in the 1960’s-1980’s, researchers frequently referred to shoulder dystocia as the “obstetrician’s greatest fear.” 

Katlin's daughter was born vaginally (9 lb 8 oz) after she refused an induction. She had a shoulder dystocia, which the doctor was able to manage. Afterwards, a nurse said she was shocked that Katlin was "allowed" to birth vaginally.

Katlin’s daughter was born vaginally (9 lb 8 oz) after she refused an induction. She had a shoulder dystocia, which the doctor was able to manage. Afterwards, a nurse said she was shocked that Katlin was “allowed” to birth vaginally.

Although big babies are at higher risk for shoulder dystocia, most cases of shoulder dystocia happen in smaller babies (Morrison et al. 1992). This is because there are many more small and normal size babies being born than big babies. Unfortunately, researchers have found that it is impossible to predict who will have shoulder dystocia and who will not (Foster et al. 2011)

In non-diabetic women, shoulder dystocia happens 0.65% of the time in babies that weigh less than 8 lbs 13 oz (6.5 cases out of 1,000 births), 6.7% of the time in babies that weigh between 8 lbs 13 oz and 9 lbs 15 oz (60 out of 1,000), and 14.5% of the time in babies that weigh 9 lbs 15 oz or greater (145 out of 1,000) (Rouse et al. 1996).

Rates of shoulder dystocia are much higher in Type I and Type II diabetes (2.2% of babies that weigh less than 8 lbs 15 oz, 13.9% of babies that weigh between 8 lb 15 oz and 9 lb 13 oz, and 52.5% of babies that weigh more than 9 lb 13 oz), and among women with gestational diabetes (Rouse et al. 1996).

I was not able to find exact numbers for the percentage of women with gestational diabetes who have shoulder dystocia, as the rates change depending on each woman’s blood sugars. However, we have strong evidence that treatment for gestational diabetes drastically cuts the chance of having a big baby and shoulder dystocia (To read more, click here).

Although most cases of shoulder dystocia can be managed by a care provider, it can sometimes result in a nerve injury in the baby called brachial plexus injury. A baby does not have to have shoulder dystocia in order to experience a brachial plexus injury. One-third of brachial plexus injuries happen when there wasn’t any shoulder dystocia. In fact, some cases of brachial plexus injury happen after elective Cesarean surgery (Rouse et al. 1996).

Some infants who have brachial plexus injury (7 out of 100) will end up with permanent nerve damage to the arm and shoulder. The remaining infants who have an injury will get better—sometimes on their own, and sometimes after therapy or surgery (Rouse et al. 1996).

Table 2

Although shoulder dystocia can be scary when it happens, there are ways care providers can help prevent and manage a shoulder dystocia. For more information, read this article on shoulder dystocia by Midwife Thinking.

Could my baby die if it experiences shoulder dystocia? Deaths from shoulder dystocia are possible but extremely rare. In 1996, researchers looked at all the studies so far that had reported the rate of death due to shoulder dystocia. In 15 studies, there were 1,100 cases of shoulder dystocia and no deaths (a death rate of 0%). In 2 other studies, the rates of infant death were 1% (1 baby out of 101 “died at delivery,” possibly due to the dystocia) and 2.5% (1 infant died out of 40 cases of shoulder dystocia) (Rouse et al. 1996).

Can big babies cause any other problems?

Laura's 3rd baby, born at home, weighed 10 lb 6 oz-- a full 2-3 pounds larger than her first two babies! Despite his being so large and having a nuchal hand, Laura did not need any stitches.

Laura’s 3rd baby, born at home, weighed 10 lb 6 oz– a full 2-3 pounds larger than her first two babies! Despite his being so large and having a nuchal hand, Laura did not need any stitches.

It is possible that women who give birth to big babies are more likely to have severe perineal tears (3rd or 4th degree). However, research studies have found conflicting results. For example, one large study found no difference in 3rd and 4th degree perineal tears between women who had big babies and those who had normal size babies (Weissmann-Brenner et al. 2012). In contrast, another study of hospital births in California during 1995-1999 found a higher rate of 4th degree tears in big babies who were born vaginally (Stotland et al. 2004). However, 4th degree tear rates in this particular study were very high, even among normal weight babies (1.5%), and the authors did not describe how many women had episiotomies, which is a leading cause of 4th degree tears.

Overall, the risk of a severe tear (3rd or 4th degree) is low in most women (anywhere from 0.2% to 0.6%), whether or not you have a big baby (Weissmann-Brenner et al. 2012). Although having a big baby may be a risk factor for severe tears, severe tears are uncommon to begin with, and a big baby is nowhere near as big a risk factor as other things like vacuum and forceps delivery. To put it into perspective, having a big baby may increase the risk of a severe tear by 3 times (so if your baseline risk was 0.2%, it would increase to 0.6%), but a vacuum delivery increases the risk by 11 times (from 0.2% to 2.2%), and the use of forceps increases the risk by 39 times (from 0.2% to 7.8%) (Sheiner et al. 2005).

Women who give birth to big babies may be at higher risk for postpartum bleeding (hemorrhage). In one large study, researchers found that women who gave birth to babies who weigh more than 9 lbs 15 oz are more likely to have postpartum hemorrhage (1.7%) compared to women who had normal size babies (0.3%) (Weissmann-Brenner et al. 2012). However, it is not clear whether this higher rate of postpartum hemorrhage is due to the big baby itself or the inductions and C-sections that care providers often recommend for a big baby (Fuchs et al. 2013)—as both these procedures can increase the risk of postpartum hemorrhage (Magann et al. 2005).

 

Amy, a well-controlled Type I diabetic, had her 3rd son (9 lbs 11 oz) after a lightning fast 25 minute labor.

Amy, a well-controlled Type I diabetic, had her 3rd son (9 lbs 11 oz) after a lightning fast 25 minute labor.

Some women have said their doctors recommend C-sections for big babies because there is a higher risk of stillbirth. However, I was not able to find any research evidence to support this claim—no evidence suggests a higher risk of stillbirth in big babies of non-diabetic women. The risk of stillbirth has historically been higher in women with Type I or Type II diabetes. However, in recent years the stillbirth rate for women with Type I or Type II diabetes has drastically declined, due to improvements in how we manage diabetes during pregnancy (Gabbe et al. 2012). As far as gestational diabetes goes, the largest study ever done on gestational diabetes found no link between gestational diabetes and stillbirth (Metzger et al. 2008).

Perhaps most importantly, when a big baby is suspected, women are more likely to experience a harmful change in how their care providers see and manage labor and delivery. This leads to a higher C-section rate and a higher rate of women inaccurately being told that labor is taking too long or the baby does not “fit.”

In fact, research has consistently shown that the care provider’s perception that a baby is big is more harmful than an actual big baby by itself. In a very important study, researchers what happened to women who were suspected of having a big baby (>8 lbs 13 oz) to what happened to women who were not suspected of having a big baby—but who ended up having one (Sadeh-Mestechkin et al. 2008). The end results were astonishing. Women who were suspected of having a big baby (and actually ended up having one) had a triple in the induction rate; more than triple the C-section rate, and a quadrupling of the maternal complication rate, compared to women who were not suspected of having a big baby but who had one anyways.

Table 3

Complications were most often due to C-sections and included bleeding (hemorrhage), wound infection, wound separation, fever, and need for antibiotics. There were no differences in shoulder dystocia between the 2 groups. In other words, when a care provider “suspected” a big baby (as compared to not knowing the baby was going to be big), this tripled the C-section rates and made mothers more likely to experience complications, without improving the health of babies (Sadeh-Mestechkin et al. 2008).

Pilar's baby was born at 41 weeks at home, weighing 10 lbs. Her labor was 12 hours (including 4 hours of pushing). She did not have any ultrasounds during her pregnancy and so they did not suspect a big baby.

Pilar’s baby was born at 41 weeks at home, weighing 10 lbs. Her labor was 12 hours (including 4 hours of pushing). She did not have any ultrasounds during her pregnancy and so they did not suspect a big baby.

Other researchers have found that when a first-time mom is incorrectly suspected of having a big baby, that care providers have less patience with labor and are more likely to recommend a C-section for stalled labor. In this study, researchers followed 340 first-time moms who were all induced at term. They compared the ultrasound estimate of the baby’s weight with the actual birth weight. When the ultrasound falsely said the baby was going to weigh more than 15% higher than it ended up weighing, physicians were more than twice as likely to diagnose “stalled labor” and perform a C-section for that reason (35%) than if there was no overestimation of weight (13%) (Blackwell et al. 2009b).

Overall, a total of 8 different studies—spanning the years 1992 to 2012—have all shown that it is the suspicion of a big baby—not big babies themselves—that leads to higher induction rates, higher C-section rates, and higher rates of stalled labor (Levine et al. 1992;Weeks et al. 1995; Parry et al. 2000; Weiner et al. 2002;Sadeh-Mestechkin et al. 2008; Blackwell et al. 2009; AW et al. 2010; Little et al. 2012).

So although big babies are at higher risk for some problems, an even bigger problem for some women is the care provider’s perception that there is a big baby. This perception—whether it is true or false—changes the way the care provider behaves, which increases the chance of bad outcomes. For most women, an ultrasound at the end of pregnancy to estimate the baby’s size increases the chance of harm to her, and does not improve the health of the baby. As the title of one research study says, “Big baby?? Better not tell!”

Assumption #2: We can tell whether a baby will be big at birth.

Reality #2: Care providers and ultrasound are equally poor at predicting whether a baby will be big at birth.

Ashley was pressured into an induction. Doctors suspected an 11 lb baby, but she ended up weighing only 7 lbs 1 oz.

Ashley was pressured into an induction. Doctors suspected an 11 lb baby, but she ended up weighing only 7 lbs 1 oz.

Time and time again, researchers have found that it is very difficult to predict a baby’s size before it is born. Although 2 out of 3 U.S. women receive an ultrasound at the end of pregnancy (Declercq et al. 2013) to “estimate the baby’s size,” ultrasound results are very unreliable.  

In 2005, researchers looked at all of the studies that had ever been done on ultrasound and estimating the baby’s weight at the end of pregnancy. They found 14 studies that looked at ultrasound and its ability to predict that a baby would weigh more than 8 lbs 13 oz. Ultrasound was only accurate 17% to 79% of the time, with most studies showing that the accuracy (“post-test probability”) was less than 50%. This means that for every 10 babies that ultrasound predicts will weigh more than 8 pounds, 13 ounces– 5 babies will weigh more than that and the other 5 will weigh less (Chauhan et al. 2005).

Ultrasound is even worse at trying to predict babies who will be born weighing 9 pounds 15 ounces or greater. In 5 studies that were done, the accuracy of ultrasounds to predict extra-large babies was only 20-30%. This means that for every 10 babies the ultrasound identified as weighing more than 9 pounds 15 ounces, only 2 to 3 babies actually weighed that much, while the other 7 to 8 babies weighed less (Chauhan et al. 2005).

The researchers found 4 studies that looked at the ability of ultrasound to predict big babies in women with diabetes. The accuracy of these ultrasounds was 61-63%, which means that for every 10 babies of diabetic women who are thought to weigh more than 8 lbs 13 oz, 6 will weigh that much and 4 will weigh less. The ultrasound test probably performs better in diabetic women simply because diabetic women are more likely to have big babies. In other words, it’s easier to predict a big baby in someone who is much more likely to have a big baby to begin with.

Care providers are equally inaccurate when it comes to estimating the size of the baby. When a care provider estimates that a baby is going to weigh more than 8 lb 13 oz, the overall accuracy is only 40-53%. This means that out of all the babies that are thought to weigh more than 8 lbs 13 oz, half will weigh more than 8 lbs 13 oz and half will weigh less. The care provider’s accuracy goes up if the woman has diabetes or is post-term, again, because the chance of having a big baby is higher among these women.

Assumption #3: Induction allows the baby to be born at a smaller weight, which helps avoid shoulder dystocia and reduces the risk of C-section.

Reality #3: Although suspected big babies who are induced are born about 3.5 ounces lighter, induction for suspected big baby does not lower the risk of shoulder dystocia, and it may increase the risk of C-section.

Julie was told through her entire pregnancy that she was having a big baby. She was induced after an ultrasound at 40 weeks 3 days because he was "big" and ended up with a C-section after a cascade of interventions and more threats about my baby being "too big."  He was 7lbs 10oz and 19.5 inches long, and spent the first three days of his life in an incubator because he wasn't ready to be born.

Julie was told through her entire pregnancy that she was having a big baby. She was induced after an ultrasound at 40 weeks 3 days because he was “big” and ended up with a C-section after a cascade of interventions and more threats about my baby being “too big.” He was 7lbs 10oz and 19.5 inches long, and spent the first three days of his life in an incubator because he wasn’t ready to be born.

Researchers have consistently found that induction for suspected big babies does not improve the health of moms or babies. In a 2009 Cochrane review, researchers (Irion and Boulvain 2000) combined 3 studies in which 372 women with suspected big babies were randomly assigned to either 1) induction or 2) waiting for normal labor. When researchers compared the induction group to the normal labor group, they found no differences in C-section rates or shoulder dystocia rates. The researchers did not look at neonatal ICU admissions, Apgar scores, death rates, perineal tears, mothers’ satisfaction with care, or any long-term outcomes.

Because Gonen (1997) was the largest study included in the Cochrane review, let’s take a closer look at it. In this study, women were included if they were at least 38 weeks, had a suspected big baby (8 lbs 13 oz to 9 lbs 15 oz), did not have gestational diabetes, and had not had a previous C-section. Less than half the women were first-time moms. Women were randomly assigned (like flipping a coin) to either immediate induction with oxytocin (sometimes with cervical ripening) or waiting for normal labor.

The results? Women in the normal labor group went into labor about 5 days later than women who were immediately induced. Although women in the normal labor group tended to have slightly bigger babies (on average 3.5 ounces or 99 grams heavier), there was no difference in shoulder dystocia or C-section rates. All 11 cases of shoulder dystocia were easily managed without any nerve damage or trauma. Two infants in the normal labor group had mild brachial plexus injury—but neither of these 2 infants had shoulder dystocia, and both injuries were only temporary.  Finally, researchers found that the ultrasound overestimated the baby’s weight 70% of the time and under-estimated the baby’s weight 28% of the time.

In summary, the researchers found that: 1) ultrasound estimation of weight was inaccurate, 2) shoulder dystocia and nerve injury were unpredictable, and 3) induction for big baby did not decrease the C-section rate or the risk of shoulder dystocia.

Although the randomized, controlled trials on induction for big baby found that induction did not hurt or help moms or babies, the overall number of women enrolled in those studies was small (less than 400 women). So it is helpful for us to look at observational studies, in which researchers followed large numbers of women with suspected big babies to see what happened.

In 2002, researchers combined the results of 9 observational studies that compared women who were induced for big baby and women who went into normal labor on their own (Sanchez-Ramos et al. 2002). Women who went into normal labor had a lower C-section rate (8% vs. 17%), a higher spontaneous vaginal birth rate (83% vs. 73%), and the same shoulder dystocia rate when they were compared to women who were induced. In other words, induction for suspected big baby increased the C-section rate and did not lower the shoulder dystocia rate.

There may be a couple of reasons why the observational studies found a higher C-section rate with induction, when the randomized, controlled trials did not. First of all, the number of women was much larger in the observational studies, which makes it easier to tell a difference in C-section rates. Second, women in the observational studies who were induced may have had other medical problems that made them more likely to end up with C-sections. Third, there were more first-time moms in the observational studies—and these moms would be more likely to end up a C-section if they are induced.

Assumption #4: Elective C-sections for big baby has benefits that outweigh the potential harms.

Reality #4: Among women who are not diabetic, it would take nearly 3,700 unnecessary C-sections to prevent one baby from having a permanent nerve injury due to shoulder dystocia. If care providers recommend an elective C-section for extra big babies (>9 lbs 15 oz), for every 3 cases of permanent nerve injury that they would prevent, there would be 1 extra maternal death. 

Jillian's 1st baby experienced a brief shoulder dystocia and so she was talked into a C-section with her second baby because the doctors were afraid of another shoulder dystocia. Her 3rd baby (pictured here) was induced 1 week early because they thought she was 11 lbs. Jillian ended up having a successful VBAC with a 7 lbs 12 oz baby-- and no shoulder dystocia.

Jillian’s 1st baby experienced a brief shoulder dystocia and so she was talked into a C-section with her second baby because the doctors were afraid of another shoulder dystocia. Her 3rd baby (pictured here) was induced 1 week early because they thought she was 11 lbs. Jillian ended up having a successful VBAC with a 7 lbs 12 oz baby– and no shoulder dystocia.

Although some care providers will recommend an induction for a big baby, many skip this step and go straight to recommending an elective Cesarean. However, no studies have ever shown that a policy of elective Cesareans for big babies improves the health of moms and babies. On the contrary, researchers have estimated that this type of approach is extremely expensive and that it would take thousands of unnecessary C-sections to prevent one case of permanent nerve injury.

In 1996, a very important study published in the Journal of the American Medical Association found that a policy of elective C-sections for all big babies was not cost-effective and that there were more potential harms than potential benefits (Rouse et al. 1996).

In this study, the researchers calculated the potential effects of 3 different types of policies:

  1. No routine ultrasounds to estimate the baby’s size
  2. Routine ultrasounds and elective C-section for babies weighing 8 lbs 13 oz or more
  3. Routine ultrasounds and elective C-section for babies weighing 9 lbs 15 oz or more.

The researchers looked at the results separately for diabetic and non-diabetic women.

The results? Among non-diabetic women, a policy of elective C-sections for all suspected big babies over 8 lbs, 13 oz puts a large number of women and babies at risk of expensive and unnecessary surgeries.  In order to prevent 1 permanent nerve injury, 2,345 women would have unnecessary C-sections at a cost of $4.9 million dollars per injury prevented (costs were estimated using year 1995 dollars).

With a policy of elective C-sections for all suspected big babies over 9 lbs 15 oz, even more women would have unnecessary surgery.  In order to prevent 1 permanent nerve injury, 3,695 women would need to undergo unnecessary C-sections at a cost of $8.7 million per injury prevented. 

After an ultrasound "confirmed" her baby was large, Heidi was told she must schedule a C-section for her second baby (she wanted a vaginal birth after Cesarean). She gave birth vaginally after pushing for 1 hour and 15 minutes.

After an ultrasound “confirmed” her baby was large, Heidi was told she must schedule a C-section for her second baby (she wanted a vaginal birth after Cesarean). She gave birth vaginally after pushing for 1 hour and 15 minutes.

The authors estimated that for every 3.2 permanent nerve injuries prevented, there would be 1 maternal death due to the increased risk of death associated with C-sections. Other possible harms associated with the elective C-section policy include higher rates of serious maternal infections, blood clot disorders, bleeding (hemorrhage) that requires blood transfusions, and newborn breathing problems.

Among diabetic women, the results were different—mostly because ultrasound is slightly more reliable at predicting big babies in women who are diabetic, and because shoulder dystocia is more common in these women as well. If diabetic women were offered an elective C-section for every baby that is suspected of weighing more than 8 pounds 13 ounces, it would take 489 unnecessary surgeries to prevent one case of permanent nerve damage. This would cost $930,000 per injury avoided. If diabetic women had an elective C-section when their babies were suspected of being 9 pounds 15 ounces or greater, it would take 443 unnecessary surgeries to prevent one case of permanent nerve injury, at a cost of $880,000 per injury avoided.

In summary, evidence does not support elective C-sections for all suspected big babies, especially among non-diabetic women. There have been no randomized, controlled trials testing this intervention. It is likely that for most non-diabetic women, the potential harms of an elective C-section for a big baby outweigh the potential benefits.

In fact, non-diabetic women may be given inaccurate information if their care providers present elective C-section as a completely “safe” or “safer” option than vaginal birth for a suspected big baby, when in fact Cesarean surgery carries much potential harm for the mom, infant, and children born in future pregnancies. To read more about the potential benefits and harms of C-section versus vaginal birth, you may want to read:

Jill says, "My first baby was 8 days late, and was 11lbs & 23.5". My second baby was also 8 days late, and was 9lbs3oz and 21.5". Both were natural, unmedicated hospital births."

Jill says, “My first baby was 8 days late, and was 11lbs & 23.5″. My second baby was also 8 days late, and was 9lbs3oz and 21.5″. Both were natural, unmedicated hospital births.”

What is the bottom line? In summary, for non-diabetic moms:

  • Ultrasounds and care providers are equally inaccurate at predicting whether or not a baby will be big. If an ultrasound or a care provider predicts a big baby, they will be wrong half the time.
  •  If a care provider thinks that you are going to have a big baby, this thought is more harmful than the actual big baby itself
    • The suspicion of a big baby leads many care providers to manage a woman’s care in a way that triples her risk of C-section and quadruples the risk of complications.
    • Because of this “suspicion problem,” ultrasounds to estimate a baby’s weight probably do more harm than good in most women.
  •  Induction for big baby does not lower the risk of shoulder dystocia and may increase the risk of C-section, especially in first-time moms
  • A policy of elective C-sections for big babies likely does more harm than good for most women
    • It would take nearly 3,700 elective C-sections to prevent one permanent case of nerve injury in babies who are suspected of weighing more than 9 pounds 15 ounces
    • For every 3 permanent nerve injuries that are prevented, there will be 1 maternal death due to the elective C-sections

For diabetic moms and moms with gestational diabetes:

  • Ultrasounds are slightly more accurate at predicting a big baby, but only because these moms are at higher risk of having a big baby to begin with
  • Elective C-sections may be more cost-effective in women who have Type I or Type II diabetes
  • Treatment for gestational diabetes drastically lowers the chance of having a big baby and shoulder dystocia
  • For information specifically on induction with gestational diabetes, read this article:

Did you like this article? Then you may like to read…

Gestational diabetes and the glucola test (Click here)

Does gestational diabetes always mean a big baby and an induction? (Click here)

What is the evidence for erythromycin eye ointment in newborns? (Click here)

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Thank you to my 2 regular physician reviewers and to Amy Romano, MSN, CNM, Co-author of Optimal Care in Childbirth: The Case for a Physiologic Approach, for their feedback on this blog post. Thank you also to my readers for contributing photos of their big (and not so big), beautiful babies! I didn’t have room to include all the photos, but check back soon for a Facebook album with everyone’s photos and stories.

References

(1993). “Multicenter randomized, controlled trial of a preterm birth prevention program. Collaborative Group on Preterm Birth Prevention.” Am J Obstet Gynecol 169(2 Pt 1): 352-366. Click here.

Blackwell, S. C., J. Refuerzo, et al. (2009). “Overestimation of fetal weight by ultrasound: does it influence the likelihood of cesarean delivery for labor arrest?” Am J Obstet Gynecol 200(3): 340 e341-343. Click here.

Chauhan, S. P., W. A. Grobman, et al. (2005). “Suspicion and treatment of the macrosomic fetus: a review.” Am J Obstet Gynecol 193(2): 332-346. Click here.

Declercq, E. R., C. Sakala, et al. (2013) “Listening to mothers III: Pregnancy and childbirth.”

Foster, E. R., K. B. Cunnane, et al. (2011). “Executive dysfunction and depressive symptoms associated with reduced participation of people with severe congestive heart failure.” Am J Occup Ther 65(3): 306-313. Click here.

Fuchs, F., J. Bouyer, et al. (2013). “Adverse maternal outcomes associated with fetal macrosomia: what are the risk factors beyond birthweight?” BMC pregnancy and childbirth 13: 90. Click here.

Gabbe, S. G., J. R. Niebyl, et al. (2012). Obstetrics: Normal and problem pregnancies, Elsevier.

Gonen, O., D. J. Rosen, et al. (1997). “Induction of labor versus expectant management in macrosomia: a randomized study.” Obstetrics and gynecology 89(6): 913-917. Click here.

Irion, O. and M. Boulvain (2000). “Induction of labour for suspected fetal macrosomia.” Cochrane Database Syst Rev(2): CD000938. Click here.

Landon, M. B., C. Y. Spong, et al. (2009). “A multicenter, randomized trial of treatment for mild gestational diabetes.” N Engl J Med 361(14): 1339-1348. Click here.

Levine, A. B., C. J. Lockwood, et al. (1992). “Sonographic diagnosis of the large for gestational age fetus at term: does it make a difference?” Obstetrics and gynecology 79(1): 55-58. Click here.

Little, S. E., A. G. Edlow, et al. (2012). “Estimated fetal weight by ultrasound: a modifiable risk factor for cesarean delivery?” Am J Obstet Gynecol 207(4): 309 e301-306. Click here.

Magann, E. F., S. Evans, et al. (2005). “Postpartum hemorrhage after vaginal birth: an analysis of risk factors.” South Med J 98(4): 419-422. Click here.

Melamed, N., Y. Yogev, et al. (2010). “Sonographic prediction of fetal macrosomia: the consequences of false diagnosis.” J Ultrasound Med 29(2): 225-230. Click here.

Metzger, B. E., L. P. Lowe, et al. (2008). “Hyperglycemia and adverse pregnancy outcomes.” N Engl J Med 358(19): 1991-2002. Click here.

Morrison, J. C., J. R. Sanders, et al. (1992). “The diagnosis and management of dystocia of the shoulder.” Surg Gynecol Obstet 175(6): 515-522. Click here.

Parry, S., C. P. Severs, et al. (2000). “Ultrasonographic prediction of fetal macrosomia. Association with cesarean delivery.” J Reprod Med 45(1): 17-22. Click here.

Rouse, D. J., J. Owen, et al. (1996). “The effectiveness and costs of elective cesarean delivery for fetal macrosomia diagnosed by ultrasound.” Jama 276(18): 1480-1486. Click here.

Sadeh-Mestechkin, D., A. Walfisch, et al. (2008). “Suspected macrosomia? Better not tell.” Arch Gynecol Obstet 278(3): 225-230. Click here.

Sanchez-Ramos, L., S. Bernstein, et al. (2002). “Expectant management versus labor induction for suspected fetal macrosomia: a systematic review.” Obstetrics and gynecology 100(5 Pt 1): 997-1002. Click here.

Sheiner, E., A. Levy, et al. (2005). “Third degree perineal tears in a university medical center where midline episiotomies are not performed.” Arch Gynecol Obstet 271(4): 307-310. Click here.

Stotland, N. E., A. B. Caughey, et al. (2004). “Risk factors and obstetric complications associated with macrosomia.” International journal of gynaecology and obstetrics 87(3): 220-226. Click here.

Weeks, J. W., T. Pitman, et al. (1995). “Fetal macrosomia: does antenatal prediction affect delivery route and birth outcome?” Am J Obstet Gynecol 173(4): 1215-1219. Click here.

Weiner, Z., I. Ben-Shlomo, et al. (2002). “Clinical and ultrasonographic weight estimation in large for gestational age fetus.” Eur J Obstet Gynecol Reprod Biol 105(1): 20-24. Click here.

Weissmann-Brenner, A., M. J. Simchen, et al. (2012). “Maternal and neonatal outcomes of macrosomic pregnancies.” Med Sci Monit 18(9): PH77-81. Click here.

 

 

 

Posted in: Big babies, C-section, Evidence based practice, Gestational diabetes, Induction, Tests during pregnancy, Ultrasound

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Group B Strep in Pregnancy: Evidence for Antibiotics and Alternatives

Group B Strep in Pregnancy: Evidence for Antibiotics and Alternatives

© By Rebecca Dekker, PhD, RN, APRN.

What is Group B Strep?

Group B Streptococcus (GBS) is a type of bacteria that can cause illness in people of all ages. In newborns, GBS is a major cause of meningitis (infection of the lining of the brain and spinal cord), pneumonia (infection of the lungs), and sepsis (infection of the blood) (CDC 1996; CDC 2005; CDC 2009).

Group B strep lives in the intestines and migrates down to the rectum, vagina, and urinary tract. All around the world, anywhere from 10-30% of pregnant women are “colonized” with or carry GBS in their bodies (Johri et al. 2006). Using a swab of the rectum and vagina, women can test positive for GBS temporarily, on-and-off, or persistently (CDC 2010).

Being colonized with GBS does not mean that a woman will develop a GBS infection. Most women with GBS do not have any GBS infections or symptoms. However, GBS can cause urinary tract infections, pre-term birth, and GBS infections in the newborn (Valkenburg-van den Berg et al. 2009; CDC 2010).

In this article, I will focus on Group B Strep in pregnancy in the United States, along with some information about other countries.

Are some women more likely to carry GBS?

Researchers have looked at the risk factors for GBS in young, non-pregnant women (Feigin, Cherry et al. 2009). Women with these factors may be more likely to carry GBS:

Ashley's baby was born with an early GBS infection. Ashley tested positive for GBS but her doctor's office forgot to give her the test results. As a result, she did not receive antibiotics during labor.

Ashley’s baby was born with an early GBS infection. Ashley tested positive for GBS but her doctor’s office forgot to give her the test results. As a result, she did not receive antibiotics during labor.

  •  African-American
  • Multiple sexual partners
  •  Male-to-female oral sex
  •  Frequent or recent sex
  •  Tampon use
  •  Infrequent handwashing
  •  Less than 20 years old

How often do newborns become infected with GBS?

There are 2 main types of GBS infection in newborns: early infection and late infection. In this article we will focus on early infection, which occurs in the first 7 days after birth. When a baby has an early GBS infection, symptoms usually appear within the first 12 hours, and almost all babies will have symptoms within 24-48 hours (CDC 2010). In a study of 148,000 infants born between 2000 and 2008, almost all of the 94 infants who developed early GBS infection were diagnosed within an hour after birth—suggesting that early GBS infection probably begins before birth (Tudela et al. 2012).

Early infection is caused by direct transfer of GBS from the mother to the baby, usually after the water breaks. The bacteria travel up from the vagina into the amniotic fluid, and the fetus may accidentally swallow some of the bacteria into the lungs—leading to an early GBS infection. Babies can also get GBS on their body (skin and mucous membranes) as they travel down the birth canal. However, most of these “colonized” infants stay healthy (CDC 2010).

In 1993-1994, the American Congress of Obstetricians and Gynecologists and the American Academy of Pediatrics recommended screening all pregnant women for GBS and treating GBS-positive women with intravenous (IV) antibiotics during labor. Since that time, we have seen a remarkable drop in early GBS infection rates in the U.S.—from 1.7 cases per 1,000 births in the early 1990’s, to 0.25 cases per 1,000 births today (CDC 2012).

If a mother who carries GBS is not treated with antibiotics during labor, the baby’s risk of becoming colonized with GBS is approximately 50% and the risk of developing a serious, life-threatening GBS infection is 1 to 2% (Boyer & Gotoff 1985; CDC 2010; Feigin, Cherry et al. 2009). As I noted earlier, being colonized is not the same thing as having an early GBS infection– most colonized babies stay healthy.

On the other hand, if a woman with GBS is treated with antibiotics during labor, the risk of her infant developing an early GBS infection drops by 80%. So for example, her risk could drop from 1% down to to 0.2%. (Ohlsson 2013)

What is the risk of death if the baby has an early GBS infection?

This photo was taken in 1985 of a baby boy who was diagnosed with a meningitis GBS infection during his first day of life. This was before antibiotics were given during labor for GBS. According to his mom, this baby was a "fighter" and miraculously survived. He was diagnosed with a seizure disorder at the age of 11.

This photo was taken in 1985 of a baby boy who was diagnosed with a meningitis GBS infection during his first day of life. This was before antibiotics were given during labor for GBS. According to his mom, this baby was a “fighter” and miraculously survived. He was diagnosed with a seizure disorder at the age of 11.

Researchers have estimated that the death rate from early GBS infection is 2 to 3% for full-term infants. This means of 100 babies who have an actual early GBS infection, 2-3 will die. Death rates from GBS are much higher (20-30%) in infants who are born at less than 33 weeks gestation (CDC 2010).

Although the death rate of GBS is relatively low, infants with early GBS infections can have long, expensive stays in the intensive care unit. Researchers have also found that up to 44% of infants who survive GBS with meningitis end up with long-term health problems, including developmental disabilities, paralysis, seizure disorder, hearing loss, vision loss, and small brains. Very little is known about the long-term health risks of infants who have GBS without meningitis, but some may have long-term developmental problems (Feigin, Cherry et al. 2009; Libster et al. 2012).

Are some newborns more likely to get early GBS disease?

The primary risk factor for early GBS infection is when the mother carries GBS. However, there are some things that increase the risk of early GBS infection:

*These are the major risk factors. About 60% infants who develop early GBS infection have no major risk factors, except for the fact that their mothers carry GBS (Schrag et al. 2002).

How accurate is testing for GBS?

Sarah chose not to get tested for GBS and gave birth at home without antibiotics.

Sarah chose not to get tested for GBS and gave birth at home without antibiotics.

The CDC recommends measuring GBS with a culture test at 35-37 weeks of pregnancy. This is done by swabbing the rectum and vagina with a Q-tip, and then waiting to see if GBS grows. It takes about 48 hours to get the results back. The goal is to get the results back before labor begins (CDC, 2010).

A culture test during labor is considered the “gold standard,” but this method is not used in practice because it takes too long to get results back. In a recent, high-quality study, researchers did the culture test twice– once at 35-36 weeks and once during labor. They compared the 35-36 week test to the gold standard.

Of the women who screened negative for GBS at 35-36 weeks, 91% were still GBS-negative when the gold standard test was done during labor. The other 9% became GBS positive. These 9% were “missed” GBS cases, meaning that these women had GBS, but most (41 out of 42) did not receive antibiotics.

Of the women who screened positive for GBS at 35-36 weeks, 84% were still GBS positive when the gold standard test was done during labor. However, 16% of the GBS-positive women became GBS-negative by the time they went into labor. These 16% received unnecessary antibiotics (Young et al. 2011).

Is there a faster test that could be used in labor?

It’s possible that a rapid-test for GBS during labor may be a better option for some women. In the same study mentioned above, researchers compared the 35-36 week culture test and the in-labor rapid test to the gold-standard test (culture during labor).

The researchers found that the 35-36 week culture test only identified 69% of the women who actually had GBS during labor. Meanwhile, the in-labor rapid test was much more sensitive—it identified 91% of women with GBS during labor (Young et al, 2011).

In a 2012 study in France, researchers followed a hospital as it switched from prenatal testing to in-labor testing for GBS. With the in-labor rapid GBS test, more mothers with GBS were identified (17% vs. 12%), there were fewer cases of early GBS infection in newborns (0.5% vs. 0.9%), and the financial cost was the same (El Helali et al. 2012).

One drawback of rapid-testing is that it can still take up to 60 minutes to get the results back, and women would have to wait to get antibiotics until the results came in (Honest et al. 2006; Young et al. 2011). The CDC says that the ideal rapid test for GBS could be done at the bedside in less than 30 minutes (CDC, 2010).

Right now there is one rapid GBS test on the market that claims it can be done within 30 minutes. However, a researcher who used this test in a clinical study says that this same test actually takes 50 minutes to carry out—5 minutes to prepare the sample, and 45 minutes to run the results (Personal communication, M. Hacker, April 2013). The price of this test is not listed online– so we don’t know if it’s affordable. Finally, researchers have not done studies yet to find out whether the rapid test is cost-effective.

What is the evidence for antibiotics during labor to prevent early GBS infection?

To answer this question, I will walk you through the most important studies that led to how we most commonly try to prevent early GBS infections in the U.S. today.

GBS emerged as a widespread threat to newborns in the early 1970’s. At that time, 1.7 of every 1,000 infants had early GBS infection (CDC 2010). In 1973, a researcher proposed giving pregnant women penicillin to stop early GBS infections in infants (Franciosi et al. 1973).

First, researchers tried giving penicillin to women before labor, but this didn’t work. Although penicillin temporarily lowered GBS levels, by the time women went into labor the GBS levels were back up again (Gardner et al. 1979).

Abbi laboring in the hospital with antibiotics for GBS.

Abbi laboring in the hospital with antibiotics for GBS.

Next, researchers tried giving antibiotics to women with GBS during labor. In the late 1980’s, three groups of researchers in the U.S., Spain, and Finland randomly assigned women with GBS to either receive IV antibiotics during labor (penicillin or ampicillin) or no antibiotics (Boyer & Gotoff 1985; Tuppurainen and Hallman 1989; Matorras et al. 1991).

In a recent Cochrane review, researchers combined the results of these 3 studies that had a total of 500 pregnant women. They found that when women with GBS had antibiotics during labor, their infants risk of catching early GBS infection dropped by 83% (Ohlsson & Shah 2013).

As the Cochrane reviewers noted, there were quite a few limitations to these 3 studies. In their summary, the reviewers said “There is no valid information from these three small, old, and biased trials to inform clinical practice.” However, this statement is biased. A more appropriate conclusion would be that there is some valid information from these studies, along with some limitations to the evidence.

Based on information from these 3 studies, in 1996, the CDC recommended 2 ways to prevent early GBS infections:

  1. The “universal approach.” Screen all pregnant women at 35-37 weeks and treat everyone who is positive with antibiotics during labor (this is the method that is currently used in the U.S.)
  2. The“risk-based approach.” Treat laboring women with antibiotics if they have one or more of these risk factors: GBS in the urine at any point in pregnancy, previously gave birth to an infant with early GBS infection, goes into labor at less than 37 weeks, has a fever during labor, or water has been broken for more than 18 hours (this is the method that is currently used in the United Kingdom)
Traci, who was GBS positive, labored without antibiotics in a hospital.

Traci, who was GBS positive, labored without antibiotics in a hospital.

In 2002, the CDC revised their guidelines to recommend the universal approach. This decision was based on an important study published in the New England Journal of Medicine (Schrag et al. 2002). In this study, researchers used CDC lab results and chart reviews to look at 629,912 live births that took place in the U.S. between the years 1998-1999.The researchers randomly selected 5,144 of these births to study, plus all 314 infants who were born with early GBS. They used hospital records to label women as receiving the universal approach (52%) or the risk-based approach (48%).

The results? There were 0.5 infants born with GBS per every 1,000 women.  Women in both groups received antibiotics about a third of the time. But women whose care providers used the universal approach had a 54% reduction in the risk of early GBS infection compared to women whose care providers used the risk-based approach. This means that the universal approach worked better than the risk-based approach.

In 2002-2003, the same group of researchers looked at 819,528 births in the U.S. to see whether the revised guidelines had been put into practice. Like the previous study, the researchers picked a random sample of women and infants to analyze, along with the 254 infants who had early GBS infection. Between 1999 and 2002, use of the universal approach rose from about 50% to 85%, and use of antibiotics during labor rose from 27% to 32%.

This time around, there were 0.32 infants born with early GBS per every 1,000 women (down from 0.5 cases per 1,000 only four years earlier). When researchers looked at the infants born at 37 weeks or later who had early GBS, only 18.0% were born to women who were not screened. Most of the cases of GBS in term infants (61%) happened in women who had been screened but tested negative for GBS. The researchers concluded that universal screening and antibiotic use cannot be expected to prevent 100% of early GBS infections, and that if we want to further lower GBS infection rates, then we will need access to rapid testing and vaccines against GBS (Van Dyke et al. 2009).

What is the best time to receive antibiotics for GBS?

Amy and her 3rd son. Amy was GBS positive but did not have antibiotics-- her son was born 27 minutes after her first real contraction!

Amy and her 3rd son. Amy was GBS positive but did not have antibiotics– her son was born 27 minutes after her first real contraction!

The CDC recommends that antibiotics be given every 4 hours, starting more than 4 hours before birth. Recent evidence supports these recommendations. In 2013, researchers looked at 7,691 live births that took place during 2003-2004 in the U.S. (randomly selected out of >600,000 births), along with 254 infants who had early GBS infection (Fairlie et al., 2013). About 1 in 3 women had antibiotics during labor (31%), and 59% of women received antibiotics more than 4 hours before birth.

When penicillin or ampicillin was given more than 4 hours before birth, it was effective 89% of the time. In contrast, giving antibiotics 2-4 hours before birth was effective 38% of the time. Antibiotics given less than 2 hours before birth were effective 47% of the time. When Clindamycin (another antibiotic) was used in place of penicillin, it worked very poorly (only 22% effective). There was no statistical difference between the 2-4 hour window and the 2-0 hour window, so even though the percentages look different, they are not statistically significant.

What are the potential benefits and harms of the universal screening and treatment approach?

Potential Benefits:

  • In clinical trials, using antibiotics (penicillin or ampicillin) decreases the risk of early GBS infection by 83%, although there are limitations to the quality of this evidence (Ohlsson 2013)
  • Penicillin rapidly crosses the placenta into the fetal circulation (at non-toxic levels) and can prevent GBS from growing in the fetus or newborn (CDC 2010; Barber et al. 2008).
  • In large studies in the U.S., the universal approach (screening and treating all GBS-positive women with antibiotics during labor) is associated with lower rates of GBS infections than giving antibiotics based on risk factors alone (Schrag et al. 2002).
  • Antibiotic resistance has not been a problem with penicillin, the drug most commonly used to prevent early GBS infection (CDC 2010).

Potential harms:

  • Although rare, severe allergic reactions in mothers have been reported. The risk is estimated to be 1 in 10,000 for a severe reaction, and 1 in 100,000 for a fatal reaction. (Weiss and Adkinson 1988).
    Jen antibiotics2_400

    Jen had a successful VBAC after laboring with antibiotics for Group B Strep.

  • There is an increase in the risk of maternal and newborn yeast infections. In one study, 15% of women who received antibiotics in labor had mother-baby yeast infections, compared to 7% of mothers who did not have antibiotics.  (Dinsmoor et al. 2005). 
  • Other potential harms have to do with side effects related to the antibiotic that is used (click on the link to see a comprehensive list of potential side effects for each antibiotic, but keep in mind that most of the serious risks are rare): Penicillin, ampicillin, cefazolin, clindaymycin, and vancomycin.
  • The potential medicalization of labor and birth (RCOG 2003).

What are the best antibiotics for someone who is allergic to penicillin?

Many women who have an allergy to penicllin can take Cefazolin instead. One advantage to Cefazolin is that (like penicillin) it crosses the placenta and reaches the fetus’s bloodstream. If a woman is at high risk for anaphylaxis with penicillin (click here to find out more), then the CDC recommends several different antibiotics instead of Cefazolin. Which antibiotic a woman can take depends on the results of her GBS lab tests. Alternative antibiotics include clindaymycin and vancomycin.

Bridget and her 11 pound son shortly after birth. Bridget was GBS positive and had 2 doses of antibiotics through a heplock. In between doses she was unhooked from the IV pole.

Bridget and her 11 pound son shortly after birth. Bridget was GBS positive and had 2 doses of antibiotics through a heplock. In between doses she was unhooked from the IV pole.

Unfortunately, clindamycin and vancomycin have never been tested in clinical trials for the prevention of early GBS infectionClindamycin faces high rates of drug resistance, barely reaches the fetal bloodstream, and should never be used unless a woman’s GBS has been specifically tested and it is known that these antibiotics will work on her particular strain of GBS. Vancomycin can be used in someone who is highly allergic to penicillin and whose GBS is resistant to clindamycin. However, Vancomycin barely crosses the placenta to get into the fetal circulation. Finally, although some care providers may use erythromycin to prevent early GBS, the CDC states that erythromycin should never be used to prevent early GBS infection (CDC, 2010; Pacifici 2006).

If I have antibiotics, does this mean I will be continuously hooked up to an IV?

No. If you use the antibiotics, you will have an IV placed, but it only takes 15-30 minutes for the antibiotics to run in.  The antibiotics are only given every 4 hours until birth, which for many women is only once or twice. When the IV is running, it should not limit positioning, walking, or even laboring in water. For the hours in between, the IV can be “hep-locked” or “saline-locked” and detached, so that you are free from the IV pole. For more information about saline locks, please read my article about saline locks during labor here.

Are there any other options?

One alternative to the universal approach is the “risk-based approach.” This is when you receive antibiotics based on other risk factors such as having a fever or your water being broken for more than 18 hours. This alternative is no longer recommended by the CDC. The number of women who receive antibiotics is roughly the same whether you choose the universal approach or the risk-based approach—about 30%. However, as already mentioned, evidence from large multi-state studies shows that in the U.S., the universal approach is more effective than giving antibiotics based on risk factors alone.

Chlorhexadine (aka Hibiclens) is a topical disinfectant that kills bacteria on contact. It binds easily to the skin and mucous membranes. In the vagina, the anti-GBS effects of chlorhexadine last from 3-6 hours.  Chlorhexadine has been shown to be safe, is easy to administer, and only costs a few cents per use (Goldenberg et al. 2006).

However, although chlorhexadine reduces the risk of a newborn being colonized with GBS, it has not been shown to decrease the risk of actual GBS infections in newborns. As I said earlier in the article, there is a difference between being colonized and being infected. Colonized babies almost always stay healthy, while infected babies are very sick, and it is thought that an actual early GBS infection occurs when the fetus swallows infected amniotic fluid into the lungs. In a Cochrane review (Stade et al. 2004), researchers combined results from 5 randomized, controlled trials that compared vaginal chlorhexadine to a placebo on outcomes of 2,190 infants born to women who were GBS positive. There was a wide range in the quality of the studies, with only one study being very high quality.

 

Lisa chose to use a hibiclens wash. She used it nightly for the last few weeks of pregnancy. During labor she washed after using the restroom and every 4 hours.

Lisa chose to use a hibiclens wash. She used it nightly for the last few weeks of pregnancy. During labor she washed after using the restroom and every 4 hours.

Even though women who used vaginal chlorhexadine reduced their infants’ risk of being colonized with GBS by 28%, there was no difference in rates of early GBS infection between women who used the chlorhexadine and those who did not. There were no cases of infant deaths from GBS in either group. The only adverse effects that were reported were stinging and irritation. The researchers called for a large clinical trial to test chlorhexadine for the prevention of early GBS.

Chlorhexadine may potentially be beneficial for women living in poor countries where access to antibiotics is limited. In their review of the literature, Goldenberg et al. (2006) found 2 studies from developing countries (Egypt and Malawi) where researchers tested chlorhexadine in the vagina  every 4 hours during labor and neonatal wipes shortly after birth. This is a lower level of evidence than the studies listed above, because neither of these were randomized, controlled trials. Instead, the researchers followed hospitals over a period of months when: 1) they did not use chlorhexadine, 2) they used chlorhexadine, and 3) they stopped using chlorhexadine. In both studies, researchers found that when chlorhexadine was used, there were immediate drops in newborn hospital admissions, newborn sepsis admissions, and newborn deaths due to infections. Unfortunately, researchers did not specifically count the number of GBS infections, just the overall number of babies who had admissions for sepsis.

So is chlorhexadine effective? The bottom line is that we don’t know with any certainty if it helps or not. Randomized, controlled trials show that in developed countries, chlorhexadine wipes during labor do not make any difference in early GBS infection rates. However, evidence from developing countries shows that chlorhexadine vaginal wipes PLUS newborn wipes may reduce sepsis rates in general. Chlorhexidine is likely better than nothing, but it cannot prevent the ascent of GBS in the amniotic fluid unless it is given before a woman’s water breaks and repeated before its effect wears off. Unlike IV antibiotics, there is no evidence that chlorhexadine can stop GBS from growing in the fetus before birth.

Garlic has antibacterial properties, and some websites recommend putting garlic in the vagina to eliminate GBS before the GBS test. However, there is very little evidence to back up this treatment. One group of researchers put garlic extract and GBS in a petri dish together (Cutler et al., 2009). They found that the garlic was able to kill the GBS within about 3 hours. However, this treatment has never been tested in people. Also, it’s important to understand that back in the 1970’s when researchers tried using penicillin during pregnancy, they found that the antibacterials temporarily lower levels of GBS, but levels almost always go up again by the time women go into labor. So by temporarily using garlic, this could help you get a negative test result, but the effect will wear off very quickly. 

Some women choose to keep garlic or chlorhexidine in the vagina for the last 4 weeks of pregnancy or use either of these treatments regularly before their water breaks and before they go into labor. It’s possible that this may help decrease GBS levels before labor. However, we do not have any research evidence yet to support this practice. This means we have little evidence about the potential benefits and harms. For example, it is possible that long-term garlic or chlorhexidine use could potentially or theoretically  have unexpected effects like premature rupture of membranes or increase other bacteria– even GBS– due to destruction of good bacteria, like lactobacilli. Until researchers examine the potential benefits and harms, there are a lot of unknowns related to this treatment.

Vaccines for GBS are under development, but are not available yet at this time (World Health Organization, 2005). There is a big push for a GBS vaccine for several reasons: 1) in-labor antibiotics do not prevent GBS infection 100% of the time (Velaphi et al., 2003), 2) in-labor antibiotics can have side effects, and 3) in-labor antibiotics do not prevent other GBS problems, such as preterm labor.

Taking probiotics (lactobacilli) is another remedy that people sometimes use to eliminate GBS in the vagina. In several studies, researchers have put vaginal lactobacilli (including a commercially available version) in a petri dish with different strains of GBS. They found that the lactobacilli strongly inhibited the growth of GBS by increasing the acidity of the environment. (Acikgov, 2005– article in Turkish; Zarate, 2006).

In a small clinical trial, researchers randomly assigned healthy, fertile (but non-pregnant) women to wear panty liners that were saturated with probiotics, or to wear placebo panty liners. The results showed that it is possible to transfer probiotics to the vagina using panty liners. The researchers also found that women who had higher levels of lactobacilli in the vagina had lower levels of GBS. However, although these results are promising, large clinical trials need to be conducted in pregnant women to determine if this is an effective way to prevent early GBS infection in newborns (Rönnqvist PD, 2007).

A few websites mention colloidal silver as a remedy for preventing GBS infection. Although silver has anti-bacterial properties, no known research studies have ever been conducted on taking colloidal silver to prevent a GBS infection—and no studies have ever looked at the safety of colloidal silver in pregnancy. The potential benefits and harms of this substance are unknown. In 1997, the FDA stated that colloidal silver is not safe or effective for any condition.

Can infants acquire a GBS infection from staff handling the newborn?

Barbara decided not to have antibiotics for GBS. Her daughter was born at home.

Barbara decided not to have antibiotics for GBS. Her daughter was born at home.

Researchers are quite certain that infants catch early GBS infections before they are born—most likely from GBS in the amniotic fluid. As mentioned earlier, almost all infants with early GBS infection show symptoms within an hour after birth. However, infants can catch “later” GBS infections from the hospital (nursery, hands of hospital staff and family members) or the community. This is one reason hand-washing is so important (Kliegman et al. 2011).

If I am GBS positive, and I don’t get the IV antibiotics for some reason, what kind of tests will my baby need to have?

As long as your baby appears to be doing well and you did not have any additional risk factors (<37 weeks, infection of the uterus, water broken >18 hours), then there is no need for your baby to have any special testing. There are some situations where the CDC recommends that a well-appearing infant have some blood tests. The CDC also  recommends 48 hours of “observation”for infants who are born to GBS positive mothers, but there is no need to separate mom and baby for this observation period. To see a flow-chart with more details about newborn testing and observation, click here.

What do national organizations have to say?

In the United States:

The U.S. Centers for Disease Control and Prevention recommends universal screening for GBS at 35-37 weeks and in-labor antibiotics for all women who test positive.

Kimberly laboring with antibiotics for GBS

Kimberly laboring with antibiotics for GBS

  • American Congress of Obstetricians and Gynecologists
  • American Academy of Pediatrics
  • American College of Nurse-Midwives
  • American Academy of Family Physicians
  • American Society for Microbiology

In the United Kingdom:

  • The United Kingdom National Screening Committee states that pregnant women in the UK should not be screened for GBS. The UK follows the risk-based approach. This includes giving antibiotics in-labor to all women who have fever, prolonged rupture of membranes >18 hours, GBS in urine at any time during pregnancy, preterm labor, or a prior infant with GBS. This means that many women who are actually GBS negative receive antibiotics directed at GBS, just based on their risk factors.  In the UK, the rate of early GBS infections is 0.5 per 1,000 births, which is slightly higher than the rate of 0.2 per 1,000 births in the U.S. In the UK, it is not considered cost effective to screen the whole population of pregnant women to lower the early GBS infection rate by 0.2-0.3 cases per 1,000.
  • The Royal College of Obstetricians does not recommend routine screening for GBS during pregnancy. However, they do state that in-labor antibiotics could be considered if GBS was detected in passing or if women have any of the risk factors listed above. Many women are already receiving antibiotics for these reasons.
  • There is controversy in the UK over the lack of access to GBS testing within the National Health Service. Group B Strep Support is a consumer-based charity that advocates for women to have access to GBS screening in the UK.

In Canada:

What is the bottom line?

  • Since two-thirds of remaining early GBS infections are now due to false negative GBS test results, in the future we may benefit from a rapid in-labor test for GBS
  • While probiotics, chlorhexadine, and garlic have the potential to reduce vaginal and newborn colonization with GBS, we do not have evidence yet to show that these strategies can prevent early GBS infections, since GBS infection usually occurs when GBS gains access to the amniotic fluid and gets into the fetus’ lungs during labor.
Ashley's baby, a survivor of GBS, healthy at 6 months old.

Ashley’s baby, a survivor of GBS, healthy at 6 months old.

I would like to acknowledge my reviewers for helping maintain the quality of articles published at Evidence Based Birth. In particular, I would like to acknowledge Dr. Jessica Illuzzi, Associate Professor of Obstetrics, Gynecology, and Reproductive Sciences at Yale School of Medicine, for her expert review and assistance in writing this article. I would also like to acknowledge my 2 regular physician reviewers, and 2 other anonymous peer reviewers (a GBS researcher and a microbiologist).

 

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You may also want to read:

The Evidence for Skin-to-Skin Care after a Cesarean

The Evidence for Erythromycin Ointment in Newborns

References

  1. Adair, C. E., L. Kowalsky, et al. (2003). “Risk factors for early-onset group B streptococcal disease in neonates: a population-based case-control study.” CMAJ 169(3): 198-203. Click here.
  2. Ackigov, Z. C., S. Gamberzade et al. (2005). “Inhibitor effect of vaginal lactobacilli on group B streptococci.” Mikrobiyol Bul 39(1): 17-23. (Article in Turkish and unable to translate). Click here.
  3. Barber, E. L., G. Zhao, et al. (2008). “Duration of intrapartum prophylaxis and concentration of penicillin G in fetal serum at delivery.” Obstetrics and gynecology 112(2 Pt 1): 265-270. Click here.
  4. Boyer, K. M. and S. P. Gotoff (1985). “Strategies for chemoprophylaxis of GBS early-onset infections.” Antibiot Chemother 35: 267-280. Click here.
  5. Centers for Disease Control and Prevention (CDC) (2009). “Trends in perinatal group B streptococcal disease- United States, 2000-2006.” MMWR Morb Mortal Wkly Rep 58: 109-112.
  6. CDC (2010). “Prevention of perinatal group b streptococcal disease.” MMWR 59: 1-32. Click here.
  7. CDC (2012). “ABCs report: Group B streptococcus, 2010.”   Retrieved March 10, 2013. Click here.
  8. CDC (1996). “Prevention of perinatal group B streptococcal disease: a public health perspective. .” MMWR Recomm Rep 45: 1-24.
  9. CDC (2005). “Early-onset and late-onset neonatal group B streptococcal disease– United States, 1996-2004.” MMWR Morb Mortal Wkly Rep 54: 1205-1208.
  10. Cutler, R. R., Odent M, et al. (2009). In vitro activity of an aqueous allicin extract and a novel allicin topical gel formulation against Lancefield group B streptococci. J Antimicrob Chemother 63(1): 151-154. Click here.
  11. Dinsmoor, M. J., R. Viloria, et al. (2005). “Use of intrapartum antibiotics and the incidence of postnatal maternal and neonatal yeast infections.” Obstetrics and gynecology 106(1): 19-22. Click here.
  12. El Helali, N., Y. Giovangrandi, et al. (2012). “Cost and effectiveness of intrapartum group B streptococcus polymerase chain reaction screening for term deliveries.” Obstetrics and gynecology 119(4): 822-829. Click here.
  13. Fairlie, T., E. R. Zell, et al. (2013). “Effectiveness of intrapartum antibiotic prophylaxis for prevention of early-onset group b streptococcal disease.” Obstetrics and gynecology 121(3): 570-577. Click here.
  14. Feigin, R. D., J. D. Cherry, et al. (2009). Textbook of Pediatric Infectious Diseases, Saunders.
  15. Franciosi, R. A., J. D. Knostman, et al. (1973). “Group B streptococcal neonatal and infant infections.” J Pediatr 82(4): 707-718. Click here.
  16. Gardner, S. E., M. D. Yow, et al. (1979). “Failure of penicillin to eradicate group B streptococcal colonization in the pregnant woman. A couple study.” Am J Obstet Gynecol 135(8): 1062-1065. Click here.
  17. Goldenberg, R. L., E. M. McClure, et al. (2006). “Use of vaginally administered chlorhexidine during labor to improve pregnancy outcomes.” Obstetrics and gynecology 107(5): 1139-1146. Click here.
  18. Heath, P. T., G. F. Balfour, et al. (2009). “Group B streptococcal disease in infants: a case control study.” Arch Dis Child 94(9): 674-680. Click here.
  19. Honest, H., S. Sharma, et al. (2006). “Rapid tests for group B Streptococcus colonization in laboring women: a systematic review.” Pediatrics 117(4): 1055-1066. Click here.
  20. Johri, A. K., L. C. Paoletti, et al. (2006). “Group B Streptococcus: global incidence and vaccine development.” Nat Rev Microbiol 4(12): 932-942. Click here.
  21. Kliegman, R. M., B. F. Stanton, et al. (2011). Nelson Textbook of Pediatrics, Saunders.
  22. Libster, R., K. M. Edwards, et al. (2012). “Long-term outcomes of group B streptococcal meningitis.” Pediatrics 130(1): e8-15. Click here.
  23. Mandell, G. L., J. E. Bennett, et al. (2010). Principles and practice of infectious diseases, Elsevier.
  24. Matorras, R., A. Garcia-Perea, et al. (1991). “Maternal colonization by group B streptococci and puerperal infection; analysis of intrapartum chemoprophylaxis.” Eur J Obstet Gynecol Reprod Biol 38(3): 203-207. Click here.
  25. Ohlsson, A. and V. S. Shah (2013). “Intrapartum antibiotics for known maternal Group B streptococcal colonization.” Cochrane Database Syst Rev 1: CD007467. Click here.
  26. Ronnqvist, P.D., U. B. Forsgren-Brusk, et al. (2006). “Lactobacilli in the female genital tract in relation to other genital microbes and vaginal pH.” Acta Obstet Gynecol Scand 85(6): 726-735. Click here.
  27. Schrag, S. J., E. R. Zell, et al. (2002). “A population-based comparison of strategies to prevent early-onset group B streptococcal disease in neonates.” N Engl J Med 347(4): 233-239. Click here.
  28. Stade, B., V. Shah, et al. (2004). “Vaginal chlorhexidine during labour to prevent early-onset neonatal group B streptococcal infection.” Cochrane Database Syst Rev(3): CD003520. Click here.
  29. Tudela, C. M., R. D. Stewart, et al. (2012). “Intrapartum evidence of early-onset group B streptococcus.” Obstetrics and gynecology 119(3): 626-629. Click here.
  30. Tuppurainen, N. and M. Hallman (1989). “Prevention of neonatal group B streptococcal disease: intrapartum detection and chemoprophylaxis of heavily colonized parturients.” Obstetrics and gynecology 73(4): 583-587. Click here.
  31. Valkenburg-van den Berg, A. W., A. J. Sprij, et al. (2009). “Association between colonization with Group B Streptococcus and preterm delivery: a systematic review.” Acta obstetricia et gynecologica Scandinavica 88(9): 958-967. Click here.
  32. Van Dyke, M. K., C. R. Phares, et al. (2009). “Evaluation of universal antenatal screening for group B streptococcus.” N Engl J Med 360(25): 2626-2636. Click here.
  33. Velaphi, S., J. D. Siegel, et al. (2003). “Early-onset group B streptococcal infection after a combined maternal and neonatal group B streptococcal chemoprophylaxis strategy.” Pediatrics 111(3): 541-547. Click here.
  34. Weiss, M. E. and N. F. Adkinson (1988). “Immediate hypersensitivity reactions to penicillin and related antibiotics.” Clin Allergy 18(6): 515-540. Click here.
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  36. Young, B. C., L. E. Dodge, et al. (2011). “Evaluation of a rapid, real-time intrapartum group B streptococcus assay.” Am J Obstet Gynecol 205(4): 372 e371-376. Click here.
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Posted in: Evidence based practice, Tests during pregnancy

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The Evidence for Doulas

The Evidence for Doulas

© 2013 by Rebecca L. Dekker, PhD, RN, APRN of www.evidencebasedbirth.com

This is an updated version of an article that was originally published in June 2012. In addition to updating this article, I partnered with Doulaville Seattle and ImprovingBirth.org to create a handout version of this article called: “Doulas and HealthCare Providers: Working Together for Better Maternal and Infant Outcomes.” To download the free handout, click on the link and it will take you to a Google document. Feel free to print  the handout and link to it on your websites. Thank you to Jenne of Doulaville for taking the lead and creating this handout for others to use!

Follow Evidence Based Birth on Facebook or subscribe to the blog (upper right hand corner of the website) to receive updates about future articles!

Photo submitted by Rebekah of Great Expectations.

Photo submitted by Rebekah of Great Expectations.

What is a doula?

According to DONA International, a doula is a professional who is trained in childbirth and provides continuous support to a mother before, during, and just after birth (postpartum douluas are not covered in this article). Doula comes from a Greek word that means “a woman who serves” or “handmaiden.”

How many women use doulas?

In a 2006 survey that took place in the U.S., only 3% of women said they used a doula during childbirth (Declerq et al., 2007).

What do doulas do?

Doulas “mother the mother.” While performing her role, a doula:

  • Provides emotional support
  • Uses comfort measures: breathing, relaxation, movement, positioning
  • Gives information
  • Continuously reassures and comforts the mother (the key word is continuous—a doula never leaves the mother’s side)
  • Helps a mother become informed about various birth choices
  • Advocates for the mother and helps facilitate communication between the mother and care provider
  • Looks after your partner as well (gives them bathroom breaks!), but their primary responsibility is to the mother
Katja says: "My husband was deployed but present via Skype for the whole thing. Thanks to my doula I was still able to have my homebirth. My daughter is a little doula-to-be."

Katja says: “My husband was deployed but present via Skype for the whole thing. Thanks to my doula I was still able to have my homebirth. My daughter is a little doula-to-be.”

It’s also important for you to understand what doulas do NOT do:

  • Doulas are NOT medical professionals
  • They do not perform clinical tasks such as vaginal exams or fetal heart monitoring
  • They do not give medical advice or diagnose conditions
  • They do not judge you for decisions that you make
  • They do not let their personal values or biases get in the way of caring for you (for example, they should not pressure you into making any decisions just because that’s what they prefer)
  • They do not take over the role of your husband or partner
  • They do not deliver the baby
  • They do not change shifts

You can read more about what doulas do and do not do in the DONA International’s standard of practice for birth doulas written here.

A doula does not leave your side and does not change shifts. Credit: Great Expectations

A doula does not leave your side and does not change shifts. Credit: Great Expectations

How is a doula different from a labor and delivery nurse or partner/spouse?

The most important thing a woman needs during labor is continuous support. This means that you have someone by your side continuously from start to finish. A doula never leaves your side. Nurses have many other responsibilities other than you. Aside from helping care for you, the nurse is communicating with your care provider, taking care of other patients, documenting care, taking breaks, and taking care of other responsibilities. A nurse’s support ends when her shift does. The doula only has one obligation the whole time she is with you—and that is YOU!

Dads and doulas can work together to make a support team for the mother. Credit: Great Expectations

Dads and doulas can work together to make a support team for the mother. Credit: Great Expectations

Sometimes people think that they don’t need a doula because their partner will be with them continuously throughout labor. Your partner is an essential support person for you to have by your side. However, your partner will need to eat and use the bathroom at times. Also, most partners have limited knowledge about birth, medical procedures, or what goes on in a hospital. Doulas and partners can work together to make up a labor support team. To read a husband’s perspective on hiring a doula, read this article from Bloom in Spokane, Washington.

So what is the evidence for doulas?

In 2012, Hodnett et al. published an updated Cochrane review on the use of continuous support for women during childbirth. They pooled the results of 22 trials that included more than 15,000 women. These women were randomized to either receive continuous, one-on-one support during labor or “usual care.” The quality of the studies was good.

"Here is a photo of me working with a wonderful mom in labor and her AMAZING partner. Any pregnant woman would be lucky to have a birth partner like him!" Credit: Samantha of Lavender Labor

“Here is a photo of me working with a wonderful mom in labor and her AMAZING partner. Any pregnant woman would be lucky to have a birth partner like him!” Credit: Samantha of Lavender Labor

Continuous support was provided either by a member of the hospital staff, such as a midwife or nurse (9 studies), women who were not part of the woman’s social network and not part of

hospital staff (doula 5 studies; childbirth educators 1 study, retired nurses 1 study), or a companion of the woman’s social network such as a female relative or the woman’s partner (6 studies). In 11 studies, the husband/partner was not allowed to be present at birth, and so continuous support was compared to no support at all. In all the other studies, the husband or partner was allowed to be present in addition to the person providing continuous labor support.

Dawn and her doula, Kate.

Dawn and her doula, Kate.

Overall, women who received continuous support were more likely to have spontaneous vaginal births and less likely to have any pain medication, epidurals, negative feelings about childbirth, vacuum or forceps-assisted births, and C-sections. In addition, their labors were shorter by about 40 minutes and their babies were less likely to have low Apgar scores at birth.

What does this mean?

It means that if you have continuous labor support (that is, someone who never leaves your side), you are statistically more likely to have better outcomes and your baby is more likely to have better outcomes! How did doulas compare to the other types of continuous support?

The researchers also looked to see if the type of support made a difference. They wanted to know—does it matter who you choose for your continuous support? Does it matter if you choose a midwife, doula, or partner for your continuous support? They were able to look at this question for 6 outcomes: use of any pain medication, use of Pitocin during labor, spontaneous vaginal birth, C-section, admission to special care nursery after birth, and negative ratings of birth experience.

Brinda with her doula and birth partner

Brinda with her doula and birth partner

For most of these outcomes,* the best results occurred when woman had continuous labor support from a doula– someone who was NOT a staff member at the hospital and who was NOT part of the woman’s social network. When continuous labor support was provided by a doula, women experienced a:

  • 31% decrease in the use of Pitocin*
  • 28% decrease in the risk of C-section*
  • 12% increase in the likelihood of a spontaneous vaginal birth*
  • 9% decrease in the use of any medications for pain relief
  • 14% decrease in the risk of newborns being admitted to a special care nursery
  • 34% decrease in the risk of being dissatisfied with the birth experience*

For four of these outcomes,* results with a doula were better than all the other types of continuous support that were studied. For the other outcomes, there was no difference between types of continuous support.

Why are doulas so effective?

A doula can act as a buffer in a harsh environment.

A doula can act as a buffer in a harsh environment.

There are 3 main reasons why we think doulas are so effective. The first reason is the “harsh environment” theory. In most developed countries, ever since birth moved out of the home and into the hospital, women have been giving birth in conditions that can often be described as harsh. In the hospital, laboring women are frequently submitted to institutional routines, high intervention rates, personnel who are strangers, lack of privacy, bright lighting, and needles. Most of us would have a hard time dealing with these conditions when we’re feeling our best. But women in labor to deal with these harsh conditions when they are in their most vulnerable state. These harsh conditions may slow down a woman’s labor and decrease the woman’s self-confidence. It is thought that a doula “buffers” this harsh environment by providing continuous support and companionship which promotes the mother’s self-esteem (Hofmeyr, Nikodem et al. 1991).

A dad says: "My experience has shown me that, whether you're giving birth in the hospital, birth center, or at home, your impact and ability to connect and support your wife during the birth process is both supported and maximized by having a doula there on your team." Credit: www.yourbirthjourney.net and Seattle Birth Photography

A dad says: “My experience has shown me that, whether you’re giving birth in the hospital, birth center, or at home, your impact and ability to connect and support your wife during the birth process is both supported and maximized by having a doula there on your team.” Credit: www.yourbirthjourney.net and Seattle Birth Photography

The third reason that doulas are effective is because doulas are a form of pain relief (Hofmeyr, 1991). With continuous support, women are less likely to request epidurals or pain medication (Hodnett, 2011). Why are women with doulas less likely to request pain medications? Well, women are less likely to request pain medications when they have a doula because they just don’t need an epidural as much! Women who have a doula are statistically more likely to feel less pain when a doula is present. Furthermore, by avoiding epidural anesthesia, women may avoid many medical interventions that often go along with an epidural, including Pitocin augmentation and continuous electronic fetal monitoring (Caton, Corry et al. 2002).

Based on reading the evidence, I have come up with a conceptual model of how doulas support influences outcomes.

A conceptual model is what researchers use to try and understand how a phenomenon works. Here is my conceptual model on the phenomenon of doula support. This model has already been translated into several different languages– please contact me if you would like to translate it into your native language.

Doula conceptual model

 

How do I find a doula?

If you’re at all on the fence about hiring a doula, you may want to interview several doulas with your partner. Childbirth Connection has a great list of interview questions for a doula. They also have a list of websites that you can use to find doulas in your area.

So what is the bottom line?

Evidence shows that the most important thing is for women to have continuous labor support from someone– whether that person is a nurse, midwife, partner, or doula. However, with several birth outcomes, doulas have a stronger effect than other types of support persons.

Download the free printable handout called “Doulas and Health Care Providers: Working Together for Better Maternal and Infant Outcomes.”

You may also want to read:

 The Evidence for Skin-to-Skin Care after a Cesarean

The Evidence for Erythromycin Ointment in Newborns

A Doula helps Change Law about Erythromycin Ointment

A Doula Facilitates Skin-to-Skin in the Operating Room

Credit: Heidi of www.yourbirthjourney.net and Seattle Birth Photography

Credit: Heidi of www.yourbirthjourney.net and Seattle Birth Photography

References:

  1. Caton, D., M. P. Corry, et al. (2002). “The nature and management of labor pain: executive summary.” Am J Obstet Gynecol 186(5 Suppl Nature): S1-15.
  2. Declercq ER, Sakala C, Corry MP, Applebaum S. (2007). “Listening to mothers II: Report of the second national U.S. survey of women’s childbearing experiences.” The Journal of Perinatal Education 16:9-14.
  3. Hodnett, E. D. (2002). “Pain and women’s satisfaction with the experience of childbirth: a systematic review.” Am J Obstet Gynecol 186(5 Suppl Nature): S160-172.
  4. Hodnett, E. D., S. Gates, et al. (2012). “Continuous support for women during childbirth.” Cochrane database of systematic reviews: CD003766.
  5. Hofmeyr, G. J., V. C. Nikodem, et al. (1991). “Companionship to modify the clinical birth environment: effects on progress and perceptions of labour, and breastfeeding.” British journal of obstetrics and gynaecology 98(8): 756-764.

Posted in: C-section, Cochrane review, Doulas, Evidence based practice

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